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It modulates the tumor microenvironment by activating NF-B signaling, which leads to the production of oncogenic cytokines and chemokines that enhance angiogenesis and recruit TAMs, particularly M2-polarized macrophages known for their tumor-supportive roles

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The more common nutritional concern is reduced intake caused by smaller meals, appetite suppression or gastrointestinal side effects

Non-cirrhotic metabolic dysfunctionassociated steatohepatitis (MASH) with moderate to advanced liver fibrosis maintenance dose: 2.4 mg injected once weekly

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