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Interestingly, Lira has also been shown to attenuate negative feedback inhibition of bile acids by inhibiting intestinal FXR activity and ultimately reduce bile acid synthesis in the liver [76]

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doi: 10.3389/fneur.2019.01143, 82 ParkS

Comparison of intravesical botulinum toxin type A injections plus hydrodistention with hydrodistention alone for the treatment of refractory interstitial cystitis/painful bladder syndrome

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